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Rifampin/Isoniazid/Pyrazinamide Oral Tablet

For tuberculosis.

Brand Name(s): Rifater

Generic Name: Rifampin/Isoniazid/Pyrazinamide

Instructions

Take the medicine with 250 mL (1 cup) of water.

Do not eat or drink for 1 hour after taking this medicine.

This medicine will work best if you take it at about the same time every day.

Keep the medicine at room temperature. Avoid heat and direct light.

Do not take this medicine with antacids.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Tell your doctor and pharmacist about all your medicines. Include prescription and over-the-counter medicines, vitamins, and herbal medicines.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

It is very important that you follow your doctor's instructions for all blood tests.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

Please check with your doctor before drinking alcohol while on this medicine.

Contact your doctor if you notice a change in the amount or darkening of your urine.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not start or stop any other medicines without first speaking to your doctor or pharmacist.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea
  • numbness or tingling in hands and feet
  • headaches
  • liver problems
  • joint or muscle pain
  • nausea and vomiting
  • red, burning, or itchy skin
  • stomach upset or abdominal pain
  • red coloring of urine, tears or sweat

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • unusual bruising or discoloration on skin
  • chest pain
  • severe, watery or bloody diarrhea
  • fever or chills
  • swelling in the neck or throat
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • shortness of breath
  • light colored stool
  • urinating less often
  • blood in urine
  • severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.